taher kouchaki tajani; Ali Mohtashami; maghsoud Amiri; Reza Ehtesham Rasi
Abstract
in this paper we have proposed a model based on Mixed Integer Non-Linear Programming for the blood supply chain under conditions of uncertainty in supply and demand, from the stage of receiving blood from volunteers to the moment of distribution in demand centers. The challenges addressed in this optimization ...
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in this paper we have proposed a model based on Mixed Integer Non-Linear Programming for the blood supply chain under conditions of uncertainty in supply and demand, from the stage of receiving blood from volunteers to the moment of distribution in demand centers. The challenges addressed in this optimization model are the reduction of blood supply chain costs along with minimizing the shortage and expiration rate of blood products. The Markov chain has been used to address the uncertainty of donor blood supply. And to estimate the needs of medical centers, the received demand is considered fuzzy. Then The proposed model is solved in small dimensions by GAMS software and in large dimensions by Bat and Whale meta-heuristic algorithms and the results are presented. In addition, a case study is presented to show the applicability of the proposed model. The results show a reduction in the level of costs as well as a reduction in the shortage and expiration of blood products in the supply chain.
