The aim of this study was to propose a comprehensive risk classification for pharmaceutical industries. Bailey’s classical strategy method was used to develop the classification. Systematic review of literature was used for identification of articles related to supply chain risk management in pharmaceutical industries. 77 articles were selected for final review. The selected articles examined in three stages of extracting and classifying the main risk groups of the supply chain (the first dimension of the conceptual framework of classification), extracting and classifying criteria for safety and security of supply chain (the second dimension of the conceptual framework of classification) and applying the two-dimensional framework of classification to identify and classify risk factors of the supply chain. Eventually 372 risk factors were identified and classified by applying the classifying frameworks to literature of pharmaceutical supply chain risk management. The proposed classification can be used as a reference classification in studies related to supply chain risks.